ARBitR: an overlap-aware genome assembly scaffolder for linked reads.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 33216122.
- Also identified by DOI 10.1093/bioinformatics/btaa975 and PMC identifier 8352505.
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Abstract
Linked genomic sequencing reads contain information that can be used to join sequences together into scaffolds in draft genome assemblies. Existing software for this purpose performs the scaffolding by joining sequences with a gap between them, not considering potential overlaps of contigs. We developed ARBitR to create scaffolds where overlaps are taken into account and show that it can accurately recreate regions where draft assemblies are broken. ARBitR is written and implemented in Python3 for Unix-based operative systems. All source code is available at https://github.com/markhilt/ARBitR under the GNU General Public License v3. Supplementary data are available at Bioinformatics online.
Medical subject headings
- High-Throughput Nucleotide Sequencing
- Software