Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 33219229.
- Also identified by DOI 10.1038/s41467-020-19802-w and PMC identifier 7679396.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Stringent COVID-19 control measures were imposed in Wuhan between January 23 and April 8, 2020. Estimates of the prevalence of infection following the release of restrictions could inform post-lockdown pandemic management. Here, we describe a city-wide SARS-CoV-2 nucleic acid screening programme between May 14 and June 1, 2020 in Wuhan. All city residents aged six years or older were eligible and 9,899,828 (92.9%) participated. No new symptomatic cases and 300 asymptomatic cases (detection rate 0.303/10,000, 95% CI 0.270-0.339/10,000) were identified. There were no positive tests amongst 1,174 close contacts of asymptomatic cases. 107 of 34,424 previously recovered COVID-19 patients tested positive again (re-positive rate 0.31%, 95% CI 0.423-0.574%). The prevalence of SARS-CoV-2 infection in Wuhan was therefore very low five to eight weeks after the end of lockdown.
Medical subject headings
- Betacoronavirus
- Coronavirus Infections
- Mass Screening
- Nucleic Acids
- Pneumonia, Viral