Treating Coronary Artery Disease: Beyond Statins, Ezetimibe, and PCSK9 Inhibition.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 33234004.
- Also identified by DOI 10.1146/annurev-med-080819-044918.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Statins, ezetimibe, and PCSK9 inhibitors are currently the standard of care for the prevention and treatment of coronary artery disease. Despite their widespread use, coronary artery disease remains the leading cause of death worldwide, a fact that pleads for the development of new protective therapies. In no small part due to advances in the field of human genetics, many new therapies targeting various lipid traits or inflammation have recently received approval from regulatory agencies such as the US Food and Drug Administration or fared favorably in clinical trials. This wave of new therapies promises to transform the care of patients at risk for life-threatening coronary events.
Medical subject headings
- Coronary Artery Disease
- Ezetimibe
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- PCSK9 Inhibitors