The rationale behind implant coatings to promote osteointegration, bone healing or regeneration.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 33257018.
- Also identified by DOI 10.1016/j.injury.2020.11.050.
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Abstract
Implant loosening, bone healing failure, implant-associated infections, and large bony defects remain challenges in orthopedic surgery. Implant surface modifications and coatings are being developed to promote osteointegration, prevent colonization by bacteria, and release bioactive factors. The following mini-review briefly discusses the clinical problem, explains the four "osteos", presents examples of coatings used for different orthopedic indications, and finally raises awareness of the coating and translational requirements.
Medical subject headings
- Osteogenesis
- Prostheses and Implants