Lipid Metabolism Gets in a JAML during Kidney Disease.
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- Record sourced from PubMed, PMID 33264600.
- Also identified by DOI 10.1016/j.cmet.2020.11.002 and PMC identifier 7978490.
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Abstract
It is still unclear if the ability of key regulators of actin cytoskeletal remodeling to influence lipid metabolism contributes to kidney injury. In this issue of Cell Metabolism, Fu et al. (2020) show that junctional adhesion molecule-like (JAML) is a novel mediator of glomerular disease progression while suggesting a direct link between defects in cell adhesion and lipotoxicity.
Medical subject headings
- Diabetes Mellitus
- Diabetic Nephropathies
- Podocytes