Pathways to Severe COVID-19 for People with Obesity.
Where this comes from
- Record sourced from PubMed, PMID 33270351.
- Also identified by DOI 10.1002/oby.23099 and PMC identifier 7753541.
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Abstract
Increased morbidity and mortality from coronavirus disease 2019 (COVID-19) in people with obesity have illuminated the intersection of obesity with impaired responses to infections. Although data on mechanisms by which COVID-19 impacts health are being rapidly generated, there is a critical need to better understand the pulmonary, vascular, metabolic, and immunologic aspects that drive the increased risk for complications from COVID-19 in people with obesity. This review provides a broad overview of the intersection between COVID-19 and the physiology of obesity in order to highlight potential mechanisms by which COVID-19 disease severity is increased by obesity and identify areas for future investigation toward developing tailored therapy for people with obesity who develop COVID-19.
Medical subject headings
- COVID-19
- Obesity