Modeling Multi-organ Infection by SARS-CoV-2 Using Stem Cell Technology.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 33275899.
- Also identified by DOI 10.1016/j.stem.2020.11.012 and PMC identifier 7713543.
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Abstract
SARS-CoV-2, the virus causing the current COVID-19 pandemic, primarily targets the airway epithelium and in lungs can lead to acute respiratory distress syndrome. Clinical studies in recent months have revealed that COVID-19 is a multi-organ disease causing characteristic complications. Stem cell models of various organ systems-most prominently, lung, gut, heart, and brain-are at the forefront of studies aimed at understanding the role of direct infection in COVID-19 multi-organ dysfunction.
Medical subject headings
- COVID-19
- Models, Biological
- Stem Cells