Neurodevelopmental Outcomes after Premedication with Atropine/Propofol vs Atropine/Atracurium/Sufentanil for Neonatal Intubation: 2-Year Follow-Up of a Randomized Clinical Trial.

Tauzin, Manon; Marchand-Martin, Laetitia; Lebeaux, Cécile; Breinig, Sophie; Claris, Olivier; Tourneux, Pierre; Alexandre, Cénéric; Levy, Corinne et al. · J Pediatr · 2021

rct · Level II

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Abstract

This study followed 173 newborn infants in the PREmedication Trial for Tracheal Intubation of the NEOnate multicenter, double-blind, randomized controlled trial of atropine-propofol vs atropine-atracurium-sufentanil for premedication before nonemergency intubation. At 2 years of corrected age, there was no significant difference between the groups in death or risk of neurodevelopmental delay assessed with the Ages and Stages Questionnaire. Trial registration Clinicaltrials.gov: NCT01490580.

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