Variables associated with insulin production in persons with type 2 diabetes treated with multiple daily insulin injections.

Westman, Klara; Imberg, Henrik; Albrektsson, Henrik; Hirsch, Irl B; Tuomilehto, Jaakko; Dahlqvist, Sofia; Lind, Marcus · Prim Care Diabetes · 2021

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Abstract

From the MDI-liraglutide study, we evaluated variables associated with endogenous insulin production in persons with multiple daily insulin injections-treated type 2 diabetes by relating C-peptide, proinsulin and proinsulin/C-peptide ratio at baseline to baseline variables. Lower insulin production was related to longer diabetes duration, shorter abdominal sagittal diameter and more glycaemic variability.

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