Estimating the herd immunity threshold by accounting for the hidden asymptomatics using a COVID-19 specific model.
other · Level V
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- Record sourced from PubMed, PMID 33326421.
- Also identified by DOI 10.1371/journal.pone.0242132 and PMC identifier 7744057.
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Abstract
A quantitative COVID-19 model that incorporates hidden asymptomatic patients is developed, and an analytic solution in parametric form is given. The model incorporates the impact of lock-down and resulting spatial migration of population due to announcement of lock-down. A method is presented for estimating the model parameters from real-world data, and it is shown that the various phases in the observed epidemiological data are captured well. It is shown that increase of infections slows down and herd immunity is achieved when active symptomatic patients are 10-25% of the population for the four countries we studied. Finally, a method for estimating the number of asymptomatic patients, who have been the key hidden link in the spread of the infections, is presented.
Medical subject headings
- COVID-19
- Immunity, Herd
- Models, Theoretical