High-sugar feeding and increasing cholesterol levels in infants.
Where this comes from
- Record sourced from PubMed, PMID 33326580.
- Also identified by DOI 10.1093/eurheartj/ehaa868.
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Abstract
Hypercholesterolaemia is an important risk factor for cardiovascular disease. Both total and LDL cholesterol levels are three-fold higher at the end of the first year of life and about four-fold higher in adulthood compared with the neonatal period. In the USA, only 25% of infants are exclusively breastfed and simple carbohydrate-rich formulas are preferentially consumed. Spikes in fasting glucose and insulin have been reported in formula-fed infants and are associated with higher levels of proprotein convertase subtilisin/kexin type 9, suggesting a potential link between high simple sugar intake and consequent increase in LDL cholesterol in early childhood.
Medical subject headings
- Cardiovascular Diseases
- Hypercholesterolemia