Predicting CAR-T cell Immunotherapy Success through ImmunoPET.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 33328345.
- Also identified by DOI 10.1158/1078-0432.CCR-20-4297 and PMC identifier 7887102.
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Abstract
Chimeric antigen receptor (CAR)-T cell therapy has generated unprecedented advances in the treatment of hematologic cancers, but readily translatable imaging approaches to visualize the <i>in vivo</i> dynamics of CAR-T cells are lacking. Noninvasive PET imaging is the ideal tool to monitor CAR-T cells.<i>See related article by Simonetta et al., p. 1058</i>.
Medical subject headings
- Hematologic Neoplasms
- Receptors, Chimeric Antigen