A Crisp(r) New Perspective on SARS-CoV-2 Biology.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 33338422.
- Also identified by DOI 10.1016/j.cell.2020.12.003 and PMC identifier 7746090.
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Abstract
Complementary genome-wide CRISPR-Cas9 screens performed by multiple groups reveal new insights into SARS-CoV-2 biology including aspects of viral entry, translation, replication, egress, and the genes regulating these processes. Comparisons with other coronaviruses enhances our understanding of the cellular life cycle of this medically important family of emerging viruses.