Parametric Sequential Method for MRI-Based Wall Shear Stress Quantification.

Shokina, Nina; Teschner, Gabriel; Bauer, Andreas; Tropea, Cameron; Egger, Herbert; Hennig, Jurgen; Krafft, Axel J · IEEE Trans Med Imaging · 2021

basic_science · Level V

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Abstract

Wall shear stress (WSS) has been suggested as a potential biomarker in various cardiovascular diseases and it can be estimated from phase-contrast Magnetic Resonance Imaging (PC-MRI) velocity measurements. We present a parametric sequential method for MRI-based WSS quantification consisting of a geometry identification and a subsequent approximation of the velocity field. This work focuses on its validation, investigating well controlled high-resolution in vitro measurements of turbulent stationary flows and physiological pulsatile flows in phantoms. Initial tests for in vivo 2D PC-MRI data of the ascending aorta of three volunteers demonstrate basic applicability of the method to in vivo.

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