Salvage Surgery Post Definitive Chemoradiotherapy and Durvalumab for Lung Cancer.

Minegishi, Kentaro; Tsubochi, Hiroyoshi; Ohno, Keisuke; Komori, Kenjiro; Ozeki, Masaki; Endo, Shunsuke · Ann Thorac Surg · 2021

case_report · Level V

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Abstract

Although concurrent chemoradiotherapy (CRT) followed by consolidation immunotherapy considerably improves the duration of survival in patients with unresectable stage III non-small cell lung cancer (NSCLC), few data are available on the management of local relapse after therapy. We present a patient with initially unresectable NSCLC who underwent a right upper lobectomy with reconstruction of the bronchus and pulmonary artery after definitive CRT, followed by consolidation durvalumab. No postoperative complications occurred, and he was recurrence-free at the 10-month follow-up. Salvage surgery might be a viable option for local relapse of NSCLC treated with definitive CRT and durvalumab.

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