U.S. COVID-19 Vaccination Challenges Go Beyond Supply.

Abstract

Currently in <i>Annals</i>, a trio of articles each takes a different route to the same conclusion: Using initial supplies of COVID-19 vaccines to immunize as many persons as possible with a single-dose regimen may achieve more benefit than reserving supplies to administer a more effective 2-dose regimen to a smaller population. The editorialist discusses factors that may impede the timely vaccination of a substantial proportion of the U.S. population and the circumstances under which the ideas posited by the 3 articles for stretching vaccine supplies may have the greatest utility.