Risk of Sexually Transmitted Zika Virus in a Cohort of Economically Disadvantaged Urban Residents.

Aguilar Ticona, Juan P; Baig, Huma; Nery, Nivison; Doss-Gollin, Simon; Sacramento, Gielson A; Adhikarla, Haritha; Muenker, M Catherine; Wunder, Elsio A et al. · J Infect Dis · 2021

prospective_cohort · Level II

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Abstract

To understand the disease burden of sexually transmitted Zika virus (ZIKV), we prospectively followed a cohort of 359 adult and adolescent residents of an urban community in Salvador, Brazil, through the 2015 ZIKV epidemic. Later, in 2017, we used a retrospective survey to associate sexual behavior during the epidemic with ZIKV infection as defined by immunoglobulin G3 NS1 enzyme-linked immunosorbent assay. We found that males who engaged in casual sexual encounters during the epidemic were more likely (adjusted odds ratio, 6.2 [95% confidence interval, 1.2-64.1]) to be ZIKV positive, suggesting that specific groups may be at increased risk of sexually transmitted infections.

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