Chemotherapy Knowledge Base Management in the Era of Precision Oncology.

Rubinstein, Samuel M; Sethi, Tarsheen; Venepalli, Neeta K; Gyawali, Bishal; Schwartz, Candice; Rivera, Donna R; Yang, Peter C; Warner, Jeremy L · JCO Clin Cancer Inform · 2021

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Abstract

Cancer medicine has grown increasingly complex in recent years with the advent of precision oncology and wide utilization of multidrug regimens. Representing this increasingly granular knowledge is a significant challenge. As users and managers of a freely available chemotherapy drug and regimen database, we describe the changes we have made to accommodate these challenges. These include the development of a domain ontology and increased granularity in the classification of cancer types on the website.

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