Osteoradionecrosis: Exposing the Evidence Not the Bone.

Frankart, Andrew J; Frankart, Michael J; Cervenka, Brian; Tang, Alice L; Krishnan, Deepak G; Takiar, Vinita · Int J Radiat Oncol Biol Phys · 2021

systematic_review · Level I

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Abstract

Osteoradionecrosis is a relatively rare but potentially morbid and costly complication of radiation therapy for head and neck cancer. Multidisciplinary diagnosis and treatment are essential. Despite evidence guiding individual aspects of care for osteoradionecrosis, there is a lack of broad consensus on the overall diagnosis and management of this condition. This study comprehensively reviews the literature, with a focus on the past 10 years, to guide evaluation and treatment.

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