Optical Navigation of the Drop-In γ-Probe as a Means to Strengthen the Connection Between Robot-Assisted and Radioguided Surgery.

Azargoshasb, Samaneh; Houwing, Krijn H M; Roos, Paul R; van Leeuwen, Sven I; Boonekamp, Michael; Mazzone, Elio; Bauwens, Kevin; Dell'Oglio, Paolo et al. · J Nucl Med · 2021

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Abstract

With translation of the Drop-In γ-probe, radioguidance has advanced into laparoscopic robot-assisted surgery. Global-positioning-system-like navigation can further enhance the symbiosis between nuclear medicine and surgery. Therefore, we developed a fluorescence-video-based tracking method that integrates the Drop-In with navigated robotic surgery. <b>Methods:</b> Fluorescent markers, integrated into the Drop-In, were automatically detected using a daVinci Firefly laparoscope. Subsequently, a declipseSPECT-navigation platform calculated the Drop-In location within the surgical field. Using a phantom (<i>n</i> = 3), we pursued robotic navigation on SPECT/CT, whereas intraoperative feasibility was validated during porcine surgery (<i>n</i> = 4). <b>Results:</b> Video-based tracking allowed for navigation of the Drop-In toward all lesions detected on SPECT/CT (external iliac and common iliac artery regions). Augmented-reality visualization in the surgical console indicated the distance to these lesions in real time, confirmed by the Drop-In readout. Porcine surgery underlined the feasibility of the concept. <b>Conclusion:</b> Optical navigation of the Drop-In probe provides a next step toward connecting nuclear medicine with robotic surgery.

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