Experimental and clinical analysis of the use of asymmetric vs symmetric polyethylene inserts in a mobile bearing total knee arthroplasty.

Abstract

This study compared the effects of symmetric and asymmetric designs for mobile bearing polyethylene insert for total knee arthroplasty (TKA), both clinically and biomechanically through experimental cadaver tests. 303 patients implanted with a mobile bearing TKA were retrospectively analyzed up to 2-year follow-up with relative scores. The same femoral and tibial components were used for all the patients; 151 patients received a Symmetric Design (SD) insert and 152 an Asymmetric Design (AD). A biomechanical experimental test was performed to improve the comprehension of the clinical results, analyzing passive squat on 5 cadaveric knee specimens: internal-external rotations of femur and tibial insert respect to the tibia tray were analyzed in native and implanted configurations (with both symmetrical and asymmetrical inserts for each specimen). After surgery, patients' average flexion improved from 105° (with preoperative extension deficit of 5°), to 115° (SD-group) and 120° (AD-group) at the 2-year follow-up. There was no postoperative extension deficit. AD-group presented better ability to perform certain routines and wasn't affected by any pain, while antero-lateral pain was reported in some SD-group patients. The experimental tests returned no statistically relevant difference in tibio-femoral flexion-extension and internal-external rotations among all the three configurations tested; a statistically significant difference is found for insert-tray internal-external rotations between SD and AD configurations; in details, the AD insert showed insert-tray angles comparable to the ones found for femoral component-tibial tray, while the SD insert returned lower angular values. Clinically and biomechanically, an asymmetric mobile bearing insert could represent a valid alternative to symmetric mobile bearing insert. III, Case-control study Retrospective comparative study.