The distribution of cellular turnover in the human body.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 33432173.
- Also identified by DOI 10.1038/s41591-020-01182-9.
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Abstract
We integrated ubiquity, mass and lifespan of all major cell types to achieve a comprehensive quantitative description of cellular turnover. We found a total cellular mass turnover of 80 ± 20 grams per day, dominated by blood cells and gut epithelial cells. In terms of cell numbers, close to 90% of the (0.33 ± 0.02) × 10<sup>12</sup> cells per day turnover was blood cells.
Medical subject headings
- Blood Cells
- Epithelial Cells