Longitudinal changes to quadriceps thickness demonstrate acute sarcopenia following admission to hospital for an exacerbation of chronic respiratory disease.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 33443216.
- Also identified by DOI 10.1136/thoraxjnl-2020-215949.
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Abstract
Acute admission to hospital for an exacerbation of chronic respiratory disease (CRD) may impair skeletal muscle mass and function. We measured quadriceps thickness (Q<sub>thick</sub>), as a surrogate marker of muscle mass, at hospital admission, discharge, 6 weeks and 3 months in 55 patients with CRD. Q<sub>thick</sub> fell by 8.3% during the period of hospitalisation, which was sustained at 6 weeks, and only partially recovered at 3 months. Sustained loss was most marked in patients readmitted during the follow-up period. Acute reduction in quadriceps muscle mass occurs during hospitalisation, with prolonged and variable recovery, which is prevented with subsequent hospital readmission.
Medical subject headings
- Patient Admission
- Quadriceps Muscle
- Respiration Disorders
- Sarcopenia