Nebulosa recovers single-cell gene expression signals by kernel density estimation.
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- Record sourced from PubMed, PMID 33459785.
- Also identified by DOI 10.1093/bioinformatics/btab003.
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Abstract
Data sparsity in single-cell experiments prevents an accurate assessment of gene expression when visualized in a low-dimensional space. Here, we introduce Nebulosa, an R package that uses weighted kernel density estimation to recover signals lost through drop-out or low expression. Nebulosa can be easily installed from www.github.com/powellgenomicslab/Nebulosa. Supplementary data are available at Bioinformatics online.