The Role of SPECT and PET in Epilepsy.

Ponisio, Maria R; Zempel, John M; Day, Brian K; Eisenman, Lawrence N; Miller-Thomas, Michelle M; Smyth, Matthew D; Hogan, R Edward · AJR Am J Roentgenol · 2021

review · Level V

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Abstract

<b>OBJECTIVE.</b> The purpose of this article is to summarize the role of molecular imaging of the brain by use of SPECT, FDG PET, and non-FDG PET radiotracers in epilepsy. <b>CONCLUSION.</b> Quantitative image analysis with PET and SPECT has increased the diagnostic utility of these modalities in localizing epileptogenic onset zones. A multi-modal platform approach integrating the functional imaging of PET and SPECT with the morphologic information from MRI in presurgical evaluation of epilepsy can greatly improve outcomes.

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