Basophils add fuel to the flame of eczema itch.

Mali, Sonali S; Bautista, Diana M · Cell · 2021

editorial · Level V

Where this comes from

Abstract

Children and adults with atopic dermatitis suffer from intractable chronic itch and can also experience acute itch flare ups that significantly increase itch intensity. In this issue of Cell, Wang et al. demonstrate that a subset of basophils activates sensory neurons to drive allergen-evoked itch flare ups in atopic dermatitis.

Medical subject headings