"Structuromics": another step toward a holistic view of the cell.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 33482097.
- Also identified by DOI 10.1016/j.cell.2020.12.030.
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Abstract
Large-scale mapping of protein structures and their different states is crucial for gaining a mechanistic understanding of proteome function and regulation. In this issue of Cell, Cappelletti et al. achieve such a feat and identify hundreds of protein structural changes in response to outside stressors, providing a rich "structuromics" resource characterizing cellular adaptation.
Medical subject headings
- Adaptation, Physiological
- Proteome