Diagnostic Accuracy of the Panbio Severe Acute Respiratory Syndrome Coronavirus 2 Antigen Rapid Test Compared with Reverse-Transcriptase Polymerase Chain Reaction Testing of Nasopharyngeal Samples in the Pediatric Population.

Villaverde, Serena; Domínguez-Rodríguez, Sara; Sabrido, Gema; Pérez-Jorge, Conchita; Plata, Marta; Romero, María Pilar; Grasa, Carlos Daniel; Jiménez, Ana Belén et al. · J Pediatr · 2021

prospective_cohort · Level II

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Abstract

We conducted a multicenter clinical validity study of the Panbio coronavirus disease 2019 Antigen Rapid Test of nasopharyngeal samples in pediatric patients with coronavirus disease 2019-compatible symptoms of ≤5 days of evolution. Our study showed limited accuracy in nasopharyngeal antigen testing: overall sensitivity was 45.4%, and 99.8% of specificity, positive-predictive value was 92.5%.

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