Disrupting enzyme fluidity.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 33492229.
- Also identified by DOI 10.7554/eLife.65221 and PMC identifier 7834015.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A combination of X-ray crystallography, NMR, and mass spectrometry has revealed how diverse small-molecule inhibitors bind Bruton's tyrosine kinase and alter the conformation of this enzyme.
Medical subject headings
- Agammaglobulinaemia Tyrosine Kinase