Label-free three-dimensional observations and quantitative characterisation of on-chip vasculogenesis using optical diffraction tomography.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 33492325.
- Also identified by DOI 10.1039/d0lc01061h.
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Abstract
Label-free, three-dimensional (3D) quantitative observations of on-chip vasculogenesis were achieved using optical diffraction tomography. Exploiting 3D refractive index maps as an intrinsic imaging contrast, the vascular structures, multicellular activities, and subcellular organelles of endothelial cells were imaged and analysed throughout vasculogenesis to characterise mature vascular networks without exogenous labelling.
Medical subject headings
- Endothelial Cells
- Tomography, Optical