Hepatic Steatosis Associated With Exposure to Elvitegravir and Raltegravir.

Kirkegaard-Klitbo, Ditte Marie; Thomsen, Magda Teresa; Gelpi, Marco; Bendtsen, Flemming; Nielsen, Susanne Dam; Benfield, Thomas · Clin Infect Dis · 2021

retrospective_cohort · Level III

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Abstract

Moderate-to-severe hepatic steatosis in people living with human immunodeficiency virus (HIV) without viral hepatitis or excessive alcohol intake was associated with cumulative exposure to stavudine, elvitegravir, and raltegravir. Prospective trials are required to establish a causal association. Clinical Trials Registration. NCT02382822.

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