Membrane Tension Locks In Pluripotency.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 33545073.
- Also identified by DOI 10.1016/j.stem.2021.01.008.
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Abstract
In this issue of Cell Stem Cell, De Belly et al. (2021) and Bergert et al. (2021) reveal that membrane tension regulates the pluripotent state via endocytosis-mediated ERK signaling. These findings advance our understanding of naive pluripotency and highlight how cell mechanics are intertwined with molecular signaling to drive cell fate decisions.
Medical subject headings
- Embryonic Stem Cells
- Signal Transduction