NSCs: Sentinel Cells of the Brain.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 33545074.
- Also identified by DOI 10.1016/j.stem.2020.11.016.
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Abstract
Adult neural stem cells (NSCs) have the ability to oscillate between activated and dormant states in response to extrinsic regulators. In this issue of Cell Stem Cell, Belenguer et al. (2020) identify a direct role for systemic TNF-α, which acts through its receptors TNFRII and TNFRI as a regulator of NSC activation and a return to quiescence, respectively.
Medical subject headings
- Adult Stem Cells
- Neural Stem Cells