Effectiveness of intervention program on the change of glycaemic control in diabetes with depression patients: A meta-analysis of randomized controlled studies.

Lu, Xiaobing; Yang, Dongying; Liang, Jiaquan; Xie, Guojun; Li, Xuesong; Xu, Caixia; Liao, Hairong; Zhou, Hui et al. · Prim Care Diabetes · 2021

meta_analysis · Level I

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Abstract

The glycaemic control of diabetes with depression was inconsistent from randomized controlled studies. This meta-analysis aimed to explore the effectiveness of intervention methods in diabetes with depression. This study systematically searched electronic databases (PubMed, EBSCO, Elsevier, Springer, Wiley, and Cochrane) for studies published up to August 17, 2020. Standardized mean difference (SMD) and 95%CI were used to evaluate the effectiveness of interventions on HbA1c. Heterogeneity was estimated using the I<sup>2</sup> statistic. Begg's test was used to assess the possible publication bias among studies. Twelve studies of 2444 cases were included in this study. The overall SMD is -0.22 and 95%CI -0.33 to -0.10 in 0-6 months of intervention group. The I<sup>2</sup> and P were 18.4% and 0.26. There are no publication bias tested (z = 0.37, P = 0.72). Cognitive behavioral therapy and mindful self-compassion might be effective method to improve glycaemic control of diabetes with depression in 0-6 months.

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