Reductions in Cardiac Structure and Function 24 Months After Spinal Cord Injury: A Cross-Sectional Study.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 33556347.
- Also identified by DOI 10.1016/j.apmr.2021.01.070 and PMC identifier 8339187.
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Abstract
To determine the alterations in cardiac structure and function that occur in the months after spinal cord injury (SCI). Cross-sectional SETTING: Rehabilitation Hospital PARTICIPANTS: Volunteers (N=29; 4 women, 25 men) between 3 and 24 months after SCI. Transthoracic echocardiography was performed on each volunteer. The relationships between time since injury and neurologic and sensory levels of injury to cardiac structure and function were assessed via multiple linear regression. Time since injury was most strongly associated with reductions in left ventricular end diastolic volume (r<sup>2</sup>=0.156; P=.034), end systolic volume (r<sup>2</sup>=0.141; P=.045), and mass (r<sup>2</sup>=0.138; P=.047). These structural changes were paralleled by reduced stroke volume (r<sup>2</sup>=0.143; P=.043) and cardiac output (r<sup>2</sup>=0.317; P=<.001). The reductions in left ventricular structure and systolic function were not differentially affected by neurologic or sensory levels of injury (P=.084-.921). These results suggest progressive reductions in left ventricular structure and systolic function between 3 and 24 months after SCI that occur independent of neurologic and sensory levels of injury.
Medical subject headings
- Cardiac Output
- Heart Ventricles
- Spinal Cord Injuries
- Ventricular Function