Serological Profiling of Group A Streptococcus Infections in Acute Rheumatic Fever.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 33639619.
- Also identified by DOI 10.1093/cid/ciab180.
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Abstract
Rheumatic fever is a serious post-infectious sequela of group A Streptococcus (GAS). Prior GAS exposures were mapped in sera using a large panel of M-type specific peptides. Rheumatic fever patients had serological evidence of significantly more GAS exposures than matched controls suggesting immune priming by repeat infections contributes to pathogenesis.
Medical subject headings
- Rheumatic Fever
- Streptococcal Infections