Clinical Efficacy of Cefixime for the Treatment of Early Syphilis.
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 33640982.
- Also identified by DOI 10.1093/cid/ciab187 and PMC identifier 8423500.
- Licence recorded as CC BY-NC-ND.
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Abstract
Safe and efficacious alternative treatment options for syphilis are necessary. This randomized, 2-arm, noncomparative pilot study evaluated the efficacy of oral cefixime 400 mg in achieving a ≥4-fold rapid plasma reagin titer decrease by 3 or 6 months after treatment. The proportion of cefixime arm participants treated successfully was 87% (95% confidence interval, 69%-100%; 13/15). Clinical Trials Registration. NCT03752112.
Medical subject headings
- Syphilis