Degradable polymeric vehicles for postoperative pain management.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 33649338.
- Also identified by DOI 10.1038/s41467-021-21438-3 and PMC identifier 7921139.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Effective control of pain management has the potential to significantly decrease the need for prescription opioids following a surgical procedure. While extended release products for pain management are available commercially, the implementation of a device that safely and reliably provides extended analgesia and is sufficiently flexible to facilitate a diverse array of release profiles would serve to advance patient comfort, quality of care and compliance following surgical procedures. Herein, we review current polymeric systems that could be utilized in new, controlled post-operative pain management devices and highlight where opportunities for improvement exist.
Medical subject headings
- Drug Delivery Systems
- Pain Management
- Postoperative Pain
- Polymers