Treatment regimens may compromise gut-microbiome-derived signatures for liver cirrhosis.

Wu, Sicheng; Jiang, Puzi; Zhao, Xing-Ming; Chen, Wei-Hua · Cell Metab · 2021

editorial · Level V

Where this comes from

Abstract

Many of the gut-microbiome-derived signatures for liver cirrhosis, especially the important ones, were likely under the influence of proton pump inhibitors (PPIs). Wu et al. suggest that drug usage is a confounding factor in metagenomics analysis that should be controlled for.

Medical subject headings