Proton pump inhibitor use status does not modify the microbiome signature for cirrhosis.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 33657386.
- Also identified by DOI 10.1016/j.cmet.2021.02.013.
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Abstract
Oh et al. address concerns about the influence of proton pump inhibitor (PPI) use on a gut microbiome signature for cirrhosis. By removing PPI using subjects from the training cohort and retraining a 19-species Random Forest model, they demonstrate the impact of PPI usage on the signature's diagnostic accuracy is minimal.
Medical subject headings
- Gastrointestinal Microbiome
- Microbiota