How does obesity promote breast cancer tumor growth?

Reitman, Marc L · Cell Metab · 2021

basic_science · Level V

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Abstract

Obesity is a risk factor for many cancers. Maguire et al. (2021) found increased creatine synthesis by the adipocytes adjacent to breast cancers in obese mice. The creatine is transported into the cancer cells, producing larger tumors, possibly due to greater energy availability.

Medical subject headings