A Niche Above: A Novel Modality of Stem Cell Regulation in Mammalian Skin Epidermis.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 33667355.
- Also identified by DOI 10.1016/j.stem.2021.02.012 and PMC identifier 9359084.
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Abstract
In this issue of Cell Stem Cell, Ning et al. (2021) demonstrate that contractility in differentiating, suprabasally located keratinocytes acts non-cell-autonomously to regulate the replication and differentiation of the stem/progenitor keratinocytes in the basal layer of epidermis. This finding expands our understanding of the niche that regulates stem/progenitor cells in skin.
Medical subject headings
- Epigenomics
- Transcription Factors