Emergence of a Severe Acute Respiratory Syndrome Coronavirus 2 Virus Variant With Novel Genomic Architecture in Hong Kong.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 33675655.
- Also identified by DOI 10.1093/cid/ciab198 and PMC identifier 7989571.
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Abstract
Throughout the coronavirus disease 2019 (COVID-19) pandemic, divergent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineages have emerged continuously, mostly through the genomic accumulation of substitutions. We report the discovery of a SARS-CoV-2 variant with a novel genomic architecture characterized by absent ORF7a, ORF7b, and ORF8, and a C-terminally modified ORF6 product resulting from partial 5'-untranslated region (UTR) duplication and transposition.
Medical subject headings
- COVID-19
- SARS-CoV-2