Defining Galactomannan Positivity in the Updated EORTC/MSGERC Consensus Definitions of Invasive Fungal Diseases.

Mercier, Toine; Castagnola, Elio; Marr, Kieren A; Wheat, L Joseph; Verweij, Paul E; Maertens, Johan A · Clin Infect Dis · 2021

expert_opinion · Level V

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Abstract

The consensus definitions of invasive fungal diseases from the EORTC/MSGERC were recently revised and updated. They now include consensus cutoff values for the galactomannan test that support the diagnosis of probable invasive aspergillosis. In this supplement article, we provide a rationale for these proposed thresholds based on the test's characteristics and performance in different patient populations and in different specimen types.

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