The characteristics of nuclear membrane fluctuations in stem cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 33715401.
- Also identified by DOI 10.1098/rsif.2020.1010 and PMC identifier 8086882.
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Abstract
We analyse the stem cell nucleus shape fluctuation spectrum obtained from optical confocal microscopy on an hour time scale with 10 s resolution. In particular, we investigate the angular and time dependencies of these fluctuations, define appropriate correlation functions that reveal the fundamentally out of equilibrium nature of the observed fluctuations as well as their global anisotropy. Langevin equations respecting the symmetry of the system allow us to model the damped oscillatory behaviour of the time correlations.
Medical subject headings
- Nuclear Envelope
- Stem Cells