Meta-analyses of gabapentinoids for pain management after knee arthroplasty: A caveat emptor? A narrative review.
meta_analysis · Level I
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- Record sourced from PubMed, PMID 33728646.
- Also identified by DOI 10.1111/aas.13820.
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Abstract
The use of gabapentinoids for perioperative pain management after total knee arthroplasty has been the subject of nine systematic reviews and meta-analyses. A critical analysis of the clinical aspects of the methodology of these publications shows major flaws which limit the interpretation for the recommended use of perioperative gabapentinoids in pain management for unilateral primary total knee arthroplasty. Consequently, readers and authors of systematic reviews and meta-analyses should critically assess the clinical aspects of the included studies.
Medical subject headings
- Arthroplasty, Replacement, Knee