Ploidy dynamics increase the risk of liver cancer initiation.
Level V
Where this comes from
- Record sourced from PubMed, PMID 33767143.
- Also identified by DOI 10.1038/s41467-021-21897-8 and PMC identifier 7994546.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Liver cancer typically arises after years of inflammatory insults to hepatocytes. These cells can change their ploidy state during health and disease. Whilst polyploidy may offer some protection, new research shows it may also promote the formation of liver tumours.
Medical subject headings
- Liver Neoplasms