Initial report of decreased SARS-CoV-2 viral load after inoculation with the BNT162b2 vaccine.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 33782619.
- Also identified by DOI 10.1038/s41591-021-01316-7.
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Abstract
Beyond their substantial protection of individual vaccinees, coronavirus disease 2019 (COVID-19) vaccines might reduce viral load in breakthrough infection and thereby further suppress onward transmission. In this analysis of a real-world dataset of positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) test results after inoculation with the BNT162b2 messenger RNA vaccine, we found that the viral load was substantially reduced for infections occurring 12-37 d after the first dose of vaccine. These reduced viral loads hint at a potentially lower infectiousness, further contributing to vaccine effect on virus spread.
Medical subject headings
- COVID-19
- COVID-19 Vaccines
- SARS-CoV-2
- Vaccination
- Viral Load