Comparison of Blood (1->3)-β-d-Glucan Levels in AIDS-Related Pneumocystis jirovecii Pneumonia and AIDS-Related Progressive Disseminated Histoplasmosis.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 33786591.
- Also identified by DOI 10.1093/cid/ciab277.
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Abstract
In this retrospective study, (1->3)-β-d-glucan (B-glucan) was an unreliable marker for AIDS-related Pneumocystis jirovecii pneumonia (PCP) because a high percentage of participants with progressive disseminated histoplasmosis and respiratory symptoms had a positive B-glucan result. Where histoplasmosis is common, attributing B-glucan positivity to PCP without further testing risks misdiagnosis.
Medical subject headings
- Acquired Immunodeficiency Syndrome
- Histoplasmosis
- Pneumocystis carinii
- Pneumonia, Pneumocystis
- beta-Glucans