New dog, old tricks: Developmental programs resurface in inflammation.

Rosenblum, Daniel; Naik, Shruti · Cell Stem Cell · 2021

editorial · Level V

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Abstract

Cellular cartography of human tissues has provided unprecedented insight into health and disease. In a recent issue of Science, Reynolds et al. (2021) use single-cell transcriptomics to define cell states and gene programs in human skin and uncover fetal programs in dermatological diseases that may fuel inflammatory pathology.

Medical subject headings